[Updated: 2025-08-11] Lacrosse teams within Section Five are generally members are in one of two leagues; the Monroe County League, the Finger Lakes League.

The Monroe County and the Finger Lakes Leagues have been around for many years and were organized by the local school districts to allow for scheduling and other purposes for many different athletic teams. They each have constitutions that govern their activity and determine their rules and membership. They are each administered by Athletic Councils which are generally made up of school officials (usually athletic directors) who meet on a regular basis to conduct the business of their leagues.

In 2004, four teams without membership in Monroe County or Finger Lakes leagues, formed the Greater Rochester Area Lacrosse League (GRALL). Their members included Aquinas, Haverling-Haverling, Livonia and McQuaid Jesuit and Avon. The league was disbanded in 2024 with most of the teams becoming independent teams.